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Clinical Studies

Cryolipolysis® reduces excess adipose tissue

Nelson AA, Wasserman D, Avram MM. Cryolipolysis® for the Reduction of Excess Adipose Tissue. Semin Cutan Med Surg.
View abstract on PubMed


Efficacy & safety demonstrated in studies

Avram MM, Harry RS. Cryolipolysis® for Subcutaneous Fat Layer Reduction. Lasers Surg Med.
View abstract on PubMed


22% reduction in “love handles” fat layer

Dover J, Burns J, Coleman S, et al. A Prospective Clinical Study of Noninvasive Cryolipolysis® for Subcutaneous Fat Layer Reduction
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Proof of concept for Cryolipolysis®

Manstein D, Laubach H, Watanabe K, et al. Selective Cryolysis: A Novel Method of Noninvasive Fat Removal. Lasers Surg Med.
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Decreases fat and changes body contour

Zelickson B, Egbert BM, Preciado J, et al. Cryolipolysis® for Noninvasive Fat Cell Destruction: Initial Results From a Pig Model. Dermatol Surg.
View abstract on PubMed


No impact on lipid & liver function

Klein KB, Zelickson B, Ropelle JG, et al. Noninvasive Cryolipolysis® for Subcutaneous Fat Reduction Does Not Affect Serum Lipid Levels or Liver Function Tests. Lasers Surg Med.
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No evidence of long-term nerve injury

Coleman SR, Sachdeva K, Egbert BM. Clinical Efficacy of Noninvasive Cryolipolysis® and Its Effects on Peripheral Nerves. Aesthetic Plast Surg.
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Visible improvement & high patient satisfaction

Dierickx CC, Mazer JM, Sand M, et al. Safety, Tolerance, and Patient Satisfaction With Noninvasive Cryolipolysis®. Dermatol Surg.
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Long-term follow-up shows lasting results

Bernstein EF. Longitudinal Evaluation of Cryolipolysis® Efficacy. J Cosmet Dermatol.
View study summary

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